For event handling, the adapter communicates with the application through WebSphere MQ queues. Make sure that the queue manager is up and running. For request processing, SOAP-HTTP is used for communication. Make sure the Tomcat application server where Qxtend is installed is up and running, and that you can reach that machine from the adapter machine. You can test this by opening a browser on the adapter machine and open the URL http://qxtendmachine:8080/qxtendserver where qxtendmachine is the host name of the machine where Tomcat is running; 8080 is valid only if you haven't changed the default in Tomcat. If this URL does not open, or if you get an error page back, that means Qxtend is not running or cannot be reached. See Qxtend documentation for details.